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EIF2AK2 anticorps (AA 449-453)
EIF2AK2
Reactivité: Humain
IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-EIF2AK2 anticorps
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Antigène
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EIF2AK2
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
Épitope
Tous les épitopes à travers EIF2AK2 Anticorps.
AA 449-453
Reactivité
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Humain
Hôte
Toutes les hôtes sur EIF2AK2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur EIF2AK2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers EIF2AK2 Anticorps
Cet anticorp EIF2AK2 est non-conjugé
Application
Tous les applications à travers EIF2AK2 Anticorps.
Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificité
The antibody detects endogenous level of total PKR protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
Immunogène
Peptide sequence around AA 449-453 (K-G-T-L-R) derived from Human PKR. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
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Information d'application
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Indications d'application
Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:100-1:200
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Détails sur EIF2AK2
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Antigène
EIF2AK2
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
Autre désignation
PKR (EIF2AK2 Produits )
Synonymes
anticorps PKR, anticorps pkr, anticorps EIF2AK2, anticorps DKFZp469K1934, anticorps EIF2AK1, anticorps PRKR, anticorps 2310047A08Rik, anticorps 4732414G15Rik, anticorps AI467567, anticorps AI747578, anticorps Pkr, anticorps Prkr, anticorps Tik, anticorps eukaryotic translation initiation factor 2 alpha kinase 2, anticorps eukaryotic translation initiation factor 2-alpha kinase 2, anticorps EIF2AK2, anticorps eif2ak2, anticorps Eif2ak2
Sujet
Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
Poids moléculaire
68 kDa
NCBI Accession
NP_001129
UniProt
P19525
Pathways
Réparation de l'ADN , ER-Nucleus Signaling , Hepatitis C
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