Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificité
The antibody detects endogenous level of total PKCth protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
Immunogène
Peptide sequence around AA 674-678 (R-L-S-F-A) derived from Human PKCth. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
anticorps PRKCT, anticorps nPKC-theta, anticorps A130035A12Rik, anticorps AW494342, anticorps PKC-0, anticorps PKC-theta, anticorps PKCtheta, anticorps Pkcq, anticorps protein kinase C theta, anticorps protein kinase C eta, anticorps protein kinase C, theta, anticorps PRKCQ, anticorps PRKCH, anticorps Prkcq
Sujet
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production.