HDAC4/HDAC5/HDAC9 anticorps (AA 244-248)

N° du produit ABIN363088

Détail du produit anti-HDAC4/HDAC5/HDAC9 anticorps

Antigène: HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)

Épitope: AA 244-248

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC4/HDAC5/HDAC9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificité: The antibody detects endogenous level of total HDAC4/HDAC5/HDAC9 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen. Specificity/Sensitivity HDAC4/HDAC5/HDAC9 (Ab-246/259/220) Antibody detects endogenous levels of total HDAC4/HDAC5/HDAC9 protein.

Immunogène: Peptide sequence around AA 244-248, 257-261, 218-222 (T-A-S-E-P) derived from Human HDAC4, HDAC5, HDAC9. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur HDAC4/HDAC5/HDAC9

Antigène: HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)

Autre désignation: HDAC4/HDAC5/HDAC9 (HDAC4/HDAC5/HDAC9 Produits)

Synonymes: anticorps AHO3, anticorps BDMR, anticorps HA6116, anticorps HD4, anticorps HDAC-4, anticorps HDAC-A, anticorps HDACA, anticorps histone deacetylase 4, anticorps HDAC4

Sujet: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Poids moléculaire: 124 kDa

NCBI Accession: NP_055522, NP_001015

UniProt: Q9UKV0