ARNT anticorps (AA 496-789)

N° du produit ABIN363204

Détail du produit anti-ARNT anticorps

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Épitope: AA 496-789

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Mouton, Porc, Singe, Furet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ARNT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP), Gel Shift (GS)

Specificité: Reacts with human HIF 1 beta /ARNT

Réactivité croisée: Souris, Boeuf (Vache), Mouton, Rat (Rattus)

Réactivité croisée (Details): Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species.

Purification: Purified (protein G)

Immunogène: Fusion protein containing amino acids 496-789 of human HIF-1 beta

Clone: H1beta234

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ChIP1:10-1:500, IHC1:100, IHC-P 1:100, WB 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS, Sodium azide 0.05 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Détails sur ARNT

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Autre désignation: Hypoxia-Inducible Factor 1-beta (ARNT Produits)

Synonymes: anticorps HIF-1-beta, anticorps HIF-1beta, anticorps HIF1-beta, anticorps HIF1B, anticorps HIF1BETA, anticorps TANGO, anticorps bHLHe2, anticorps D3Ertd557e, anticorps Drnt, anticorps ESTM42, anticorps Hif1b, anticorps W08714, anticorps mKIAA4051, anticorps Arnt1, anticorps ARNT, anticorps zgc:136664, anticorps arnt1, anticorps hif1b, anticorps tango, anticorps xArnt, anticorps hif1beta, anticorps hif-1beta, anticorps arnt.2, anticorps MGC68805, anticorps aryl hydrocarbon receptor nuclear translocator, anticorps aryl hydrocarbon receptor nuclear translocator S homeolog, anticorps ARNT, anticorps Arnt, anticorps arnt, anticorps arnt.S

Sujet: HIF-1 is a heterodimer composed of HIF-1 alpha and HIF-1 beta subunits which are bHLH proteins of PAS (PER, ARNT, SIM) family. HIF-1 beta forms heterodimer with AHR, AHRR, HIF1 alpha and EPAS1/HIF2 alpha as well as with other bHLH proteins and its dimerization is required for efficient DNA binding. Interact with TACC3 and NOCA7.

ID gène: 405

UniProt: P27540

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg