ARNT anticorps (AA 496-789)

N° du produit ABIN363204

Cet anticorps anti-ARNT Monoclonal Souris (Clone H1beta234) (ABIN363204) détecte spécifiquement ARNT dans WB, IHC, IP, IHC (p), ChIP et GS. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc, Mouton, Singe et Furet.

Aperçu rapide pour ARNT anticorps (AA 496-789) (ABIN363204)

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Mouton, Singe, Furet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ARNT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP), Gel Shift (GS)

Clone: H1beta234

Détail du produit anti-ARNT anticorps

Épitope: AA 496-789

Specificité: Reacts with human HIF 1 beta /ARNT

Réactivité croisée: Souris, Boeuf (Vache), Mouton, Rat (Rattus)

Réactivité croisée (Details): Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species.

Purification: Purified (protein G)

Immunogène: Fusion protein containing amino acids 496-789 of human HIF-1 beta

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ChIP1:10-1:500, IHC1:100, IHC-P 1:100, WB 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS, Sodium azide 0.05 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Détails sur ARNT

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Autre désignation: Hypoxia-Inducible Factor 1-beta

Sujet: HIF-1 is a heterodimer composed of HIF-1 alpha and HIF-1 beta subunits which are bHLH proteins of PAS (PER, ARNT, SIM) family. HIF-1 beta forms heterodimer with AHR, AHRR, HIF1 alpha and EPAS1/HIF2 alpha as well as with other bHLH proteins and its dimerization is required for efficient DNA binding. Interact with TACC3 and NOCA7.

ID gène: 405

UniProt: P27540

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg