AQP2 anticorps (N-Term)
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- Antigène Voir toutes AQP2 Anticorps
- AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AQP2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes Aquaporin 2 (N-term).
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Immunoaffinity Chromatography.
- Immunogène
- Synthetic peptide corresponding to N-terminal residues of Human Aquaporin 2.
- Isotype
- IgG
- Top Product
- Discover our top product AQP2 Anticorps primaire
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- Indications d'application
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Immunohistochemistry on Paraffin Sections: 20 μg/mL. Western Blot: 1 μg/mL. ELISA: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))
- Autre désignation
- Aquaporin-2 (AQP2 Produits)
- Synonymes
- anticorps AQP-CD, anticorps WCH-CD, anticorps cph, anticorps jpk, anticorps AQP-2, anticorps aquaporin-2, anticorps aquaporin 2, anticorps aquaporin 2 (collecting duct), anticorps Aqp2, anticorps AQP2
- Sujet
- Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein aquaporins. Aquaporin 0, and Aquaporin 1 have been the foundation of the growing family of aquaporins. The lens specific Aquaporin 0 represents up to 80 % of total lens membrane protein. Defects in Aquaporin 0 are a cause of autosomal dominant cataract. The lens opacity mutation is an AA substitution that inhibits targeting of MIP to the cell membrane. Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family. Aquaporin families of proteins are predicted to contain six transmembrane domains. The N and C terminus are predicted to be cytoplasmic. Aquaporin 2 is located in the collecting tubule.Synonyms: ADH water channel, AQP-CD, AQP2, Aquaporin-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct
- Poids moléculaire
- 29 kDa.
- ID gène
- 359
- NCBI Accession
- NP_000477
- UniProt
- P41181
- Pathways
- Response to Water Deprivation
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