SLC6A3 anticorps (N-Term)

N° du produit ABIN372309

Détail du produit anti-SLC6A3 anticorps

Antigène: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC6A3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes SLC6A3/DAT1 (N-term).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide corresponding to N-terminal residues of Human DAT (Sodium-dependent Dopamine Transporter).

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 20 μg/mL. Western Blot: 1 μg/mL. ELISA: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur SLC6A3

Antigène: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Autre désignation: SLC6A3 / DAT (SLC6A3 Produits)

Synonymes: anticorps DAT, anticorps SLC6A3, anticorps Dat1, anticorps DAT1, anticorps PKDYS, anticorps solute carrier family 6 member 3, anticorps solute carrier family 6 (neurotransmitter transporter), member 3, anticorps Sodium-dependent dopamine transporter, anticorps solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, anticorps SLC6A3, anticorps slc6a3, anticorps dat-1, anticorps Slc6a3

Sujet: Plasmalemmal neurotransmitter transporters sequester synaptic and peri synaptic transmitter into presynaptic elements. The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. Levels of DAT protein expression are altered by chronic drug administration. The activity of the DAT reuptake carrier is sodium dependent, and it is suspected to play a role in such neurologic and psychiatric disorders as Parkinson's disease, Tourette's disease, schizophrenia, and addiction. It is a 12 transmembrane domain transporter with the N and C terminal regions located within the cytoplasm.Synonyms: DA transporter, DAT1, Sodium-dependent dopamine transporter, Solute carrier family 6 member 3

Poids moléculaire: 68 kDa.

ID gène: 6531

NCBI Accession: NP_001035

UniProt: Q01959

Pathways: Dopaminergic Neurogenesis