ABCC5
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
ELISA: 1/32000. Western Blot: 0.5-1.5 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
Tris saline buffer, pH 7.3 containing 0.02 % Sodium Azide and 0.5 % BSA as stabilizer.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Antigène
ABCC5
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
anticorps ABC33, anticorps EST277145, anticorps MOAT-C, anticorps MOATC, anticorps MRP5, anticorps SMRP, anticorps pABC11, anticorps 2900011L11Rik, anticorps AI132311, anticorps Abcc5a, anticorps Abcc5b, anticorps Mrp5, anticorps abc33, anticorps abcc5, anticorps moat-c, anticorps moatc, anticorps mrp5, anticorps pabc11, anticorps smrp, anticorps ATP binding cassette subfamily C member 5, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 5, anticorps ATP binding cassette subfamily C member 5 L homeolog, anticorps ABCC5, anticorps Abcc5, anticorps abcc5.L
Sujet
MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.Synonyms: ATP-binding cassette sub-family C member 5, MOAT-C, Multi-specific organic anion transporter C, Multidrug resistance-associated protein 5, SMRP, pABC11