SLC6A1 anticorps (C-Term)
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- Antigène Voir toutes SLC6A1 (GAT1) Anticorps
- SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))
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Épitope
- C-Term
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Reactivité
- Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLC6A1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Specific for the ~67k GAT-1 protein. Immunolabeling is blocked by the peptide used as antigen.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Rat. - Purification
- Affinity Chromatography.
- Immunogène
- Peptide corresponding to amino acid residues from the C-terminal region of rat GAT-1.
- Isotype
- IgG
- Top Product
- Discover our top product GAT1 Anticorps primaire
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- Indications d'application
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Western Blot: 1/1000. Immunohistochemitsry: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Antigène
- SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))
- Autre désignation
- GAT1 / SLC6A1 (GAT1 Produits)
- Synonymes
- anticorps GABATHG, anticorps GABATR, anticorps GAT1, anticorps A730043E01, anticorps GAT-1, anticorps Gabt, anticorps Gabt1, anticorps Gat1, anticorps XT-1, anticorps Xtrp1, anticorps si:ch211-280e18.1, anticorps si:dkey-164m14.1, anticorps slc6a1, anticorps solute carrier family 6 member 1, anticorps solute carrier family 6 (neurotransmitter transporter, GABA), member 1, anticorps solute carrier family 6 (neurotransmitter transporter, GABA), member 1, like, anticorps GABA neurotransmitter transporter 1, anticorps SLC6A1, anticorps Slc6a1, anticorps slc6a1l, anticorps slc6a1
- Sujet
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).Synonyms: GABA transporter 1, GABATR, GABT1, GAT-1, Sodium- and chloride-dependent GABA transporter 1, Solute carrier family 6 member 1
- ID gène
- 79212
- NCBI Accession
- NP_077347
- UniProt
- P23978
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