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TAO Kinase 2 anticorps (pSer181)
TAOK2
Reactivité: Humain, Souris, Rat, Chien, Xenopus laevis, Pinson, Poisson zèbre (Danio rerio)
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-TAO Kinase 2 anticorps
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Antigène
Voir toutes TAO Kinase 2 (TAOK2) Anticorps
TAO Kinase 2 (TAOK2)
Épitope
Tous les épitopes à travers TAO Kinase 2 Anticorps.
pSer181
Reactivité
Humain, Souris, Rat, Chien, Xenopus laevis, Pinson, Poisson zèbre (Danio rerio)
Hôte
Toutes les hôtes sur TAO Kinase 2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur TAO Kinase 2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers TAO Kinase 2 Anticorps
Cet anticorp TAO Kinase 2 est non-conjugé
Application
Tous les applications à travers TAO Kinase 2 Anticorps.
Western Blotting (WB)
Specificité
Specific for the ~120k TAO2 phosphorylated at Ser181 in Western blots. Immunolabeling is completely eliminated by treatment with lambda-phosphatase.
Réactivité croisée (Details)
Species reactivity (expected):Canine, Finch, Xenopus and Zebrafish. Species reactivity (tested):Human, Mouse and Rat.
Purification
Affinity Chromatography via sequential chromatography on phospho- and dephosphopeptide affinity columns.
Immunogène
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser181 of TAO2.
Isotype
IgG
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Discover our top product TAOK2 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Western blot: 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store the antibody undiluted (in aliquots) at-20 °C.
Détails sur TAO Kinase 2
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Antigène
TAO Kinase 2 (TAOK2)
Abstract
TAOK2 Produits
Synonymes
anticorps MAP3K17, anticorps PSK, anticorps PSK1, anticorps PSK1-BETA, anticorps TAO1, anticorps TAO2, anticorps Tao2, anticorps 1110033K02Rik, anticorps B230344N16, anticorps mKIAA0881, anticorps TAOK2, anticorps map3k17, anticorps psk, anticorps psk1, anticorps tao1, anticorps tao2, anticorps TAO kinase 2, anticorps TAO kinase 2 L homeolog, anticorps serine/threonine-protein kinase TAO2, anticorps TAOK2, anticorps Taok2, anticorps taok2.L, anticorps taok2, anticorps LOC100085396
Sujet
In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999, Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.Synonyms: KFC-C, KIAA0881, Kinase from chicken homolog C, MAP3K17, PSK-1, PSK1, Prostate-derived STE20-like kinase 1, Serine/threonine-protein kinase TAO2, Thousand and one amino acid protein 2, UNQ2971/PRO7431
ID gène
9344
NCBI Accession
NP_004774
UniProt
Q9UL54
Pathways
Cell-Cell Junction Organization
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