CBL anticorps (C-Term)
-
- Antigène Voir toutes CBL Anticorps
- CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
-
Épitope
- C-Term
-
Reactivité
- Humain, Souris, Rat, Chien, Porc, Boeuf (Vache)
-
Hôte
- Chèvre
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CBL est non-conjugé
-
Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Séquence
- C-REFVSISSPA HVAT
- Specificité
- This antibody detects RNF55 / CBL at C-term.
- Réactivité croisée (Details)
-
Species reactivity (expected):Human, Rat, Dog, Pig, Cow.
Species reactivity (tested):Mouse. - Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
- Immunogène
- Peptide from C Terminus of the protein sequence according to NP_005179.2 Genename: CBL
- Top Product
- Discover our top product CBL Anticorps primaire
-
-
- Indications d'application
-
Peptide ELISA: Limit dilution 1: 32000. Western blot: 1-3 μg/mL. Approx 120 kDa band seen in 3T3 lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
- Autre désignation
- CBL / RNF55 (CBL Produits)
- Synonymes
- anticorps 4732447J05Rik, anticorps Cbl-2, anticorps c-Cbl, anticorps cbl, anticorps C-CBL, anticorps CBL2, anticorps FRA11B, anticorps NSLL, anticorps RNF55, anticorps c-cbl-like, anticorps RGD1561386, anticorps Casitas B-lineage lymphoma, anticorps Cbl proto-oncogene, anticorps Cbl, anticorps CBL
- Sujet
- Cbl (also designated the c-Cbl proto-oncogene, E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene and RING finger protein 55) has been identified as the cellular homolog of the v-Cbl oncogene isolated from an NFS/N mouse that developed a pre-B cell lymphoma following infection with the replication-competent Cas Br-M murine leukemic virus. c-Cbl is expressed at relatively high levels in a wide range of hematopoietic tumor cell lines as well as in normal tissues such as thymus and testis. The c-Cbl gene product has been identified as a cytoplasmic protein with apparent DNA binding and dimerization domains characteristic of transcription factors. A single c-Cbl locus termed CBL2 has been mapped to human chromosome 11q23. This region of chromosome 11 is involved in translocations and deletions in a broad range of leukemias, c-Cbl has been found to be translocated from chromosome 11 in leukemias with either t(4,11) or t(11,14) abnormalities.Synonyms: CBL2, Casitas B-lineage lymphoma proto-oncogene, E3 ubiquitin-protein ligase CBL, Proto-oncogene c-CBL, RING finger protein 55, Signal transduction protein CBL, c-CBL
- ID gène
- 867
- NCBI Accession
- NP_005179
- UniProt
- P22681
- Pathways
- TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals
-