DAP3 anticorps (C-Term)
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- Antigène Voir toutes DAP3 Anticorps
- DAP3 (Death-Associated Protein 3 (DAP3))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DAP3 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Séquence
- NPSLLERHCA YL
- Specificité
- This antibody is expected to recognise isoform 1 (NP_387506.1), isoform 2 (NP_001186779.1) and isoform 3 (NP_001186780.1). Reported variants represent identical protein (NP_387506.1, NP_004623.1, NP_001186778.1).
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- Immunogène
- Peptide from C Terminus of the protein sequence according to NP_387506.1, NP_004623.1 Genename: DAP3
- Top Product
- Discover our top product DAP3 Anticorps primaire
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- Indications d'application
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Peptide ELISA: 1/16000. Western blot: 1 - 3 μg/mL. Approx 40-45 kDa band seen in HeLa lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- DAP3 (Death-Associated Protein 3 (DAP3))
- Autre désignation
- DAP3 / MRPS29 (DAP3 Produits)
- Synonymes
- anticorps DAP-3, anticorps MRP-S29, anticorps MRPS29, anticorps bMRP-10, anticorps 4921514D13Rik, anticorps im:6905684, anticorps death associated protein 3, anticorps DAP3, anticorps Dap3, anticorps dap3
- Sujet
- Death Associated Protein 3 (DAP3) is a 46 kDa protein carrying a potential nucleotide binding motif (P-loop) at its N-terminal region. The protein is widely expressed, and the expression is upregulated during membrane-receptor mediated apoptosis. In interferon-gamma and Fas induced apoptosis, DAP3 acts as a positive mediator by functioning downstream of the receptor signaling complex and upstream of the effector caspases. However, the mechanism for its function is largely unknown. Interestingly, the N-terminal 230 amino acid fragment of DAP3 alone protects cells from Fas induced cell death. The same region of DAP3 also serves as a binding site for the glucocorticoid receptor and mediates receptor functions.Synonyms: 28S ribosomal protein S29 mitochondrial, DAP-3, Death-associated protein 3, Ionizing radiation resistance conferring protein, MRP-S29
- ID gène
- 7818
- NCBI Accession
- NP_387506
- UniProt
- P51398
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