Peptide ELISA: Limit dilution 1: 16000. Western blot: 1-3 μg/mL. Approx 40-45 kDa band observed in Human Liver lysate (predictedMW of 35 kDa according to NP_056442.1). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
Antigène
LDLRAP1
(Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
anticorps ARH, anticorps ARH1, anticorps ARH2, anticorps FHCB1, anticorps FHCB2, anticorps AA691260, anticorps Arh, anticorps Arh1, anticorps RGD1563417, anticorps arh, anticorps arh1, anticorps arh2, anticorps fhcb1, anticorps fhcb2, anticorps xptb, anticorps LDLRAP1, anticorps ldlrap1, anticorps sb:cb50, anticorps zgc:56121, anticorps zgc:158745, anticorps low density lipoprotein receptor adaptor protein 1, anticorps low density lipoprotein receptor adaptor protein 1 L homeolog, anticorps low density lipoprotein receptor adaptor protein 1 S homeolog, anticorps low density lipoprotein receptor adaptor protein 1a, anticorps low density lipoprotein receptor adaptor protein 1b, anticorps LDLRAP1, anticorps Ldlrap1, anticorps ldlrap1, anticorps ldlrap1.L, anticorps ldlrap1.S, anticorps ldlrap1a, anticorps ldlrap1b
Sujet
ARH is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.Synonyms: ARH, Autosomal recessive hypercholesterolemia protein, LDLRAP1, Low density lipoprotein receptor adapter protein 1