MYRIP anticorps (C-Term)

N° du produit ABIN374340

Détail du produit anti-MYRIP anticorps

Antigène: MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp MYRIP est non-conjugé

Application: Western Blotting (WB)

Séquence: C-KDLMEPALES AVMY

Specificité: This antibody detects MYRIP at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_056275.2 Genename: MYRIP

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1/64000. Western blot: Use at 0.1-0.3 μg/mL. Approx 90 kDa band observed in Human Brain(Amygdala) lysates (Calculated MW of 95.0 kDa according to NP_056275.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris-saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Détails sur MYRIP

Antigène: MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))

Autre désignation: MYRIP (MYRIP Produits)

Synonymes: anticorps SLAC2-C, anticorps SLAC2C, anticorps A230081N12Rik, anticorps Slac2-c, anticorps Slac2c, anticorps MYRIP, anticorps si:dkey-189e1.4, anticorps LOC100156583, anticorps myosin VIIA and Rab interacting protein, anticorps MYRIP, anticorps Myrip, anticorps myrip

Sujet: A molecular complex composed of Rab27A, MYRIP and myosin VIIa bridges retinal melanosomes to the actin cytoskeleton and thereby mediates the local trafficking of these organelles. The defect of this molecular complex is likely to account for the perinuclear mislocalization of the melanosomes observed in the retinal pigment epithelium cells of myosin VIIa-defective mice.Synonyms: Exophilin-8, Myosin-VIIa- and Rab-interacting protein, Rab effector MyRIP, SLAC2C, SlaC2-c, Slp homolog lacking C2 domains c

ID gène: 25924

NCBI Accession: NP_056275

UniProt: Q8NFW9

Pathways: Positive Regulation of Peptide Hormone Secretion