Paired Box 3 anticorps (N-Term)
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- Antigène Voir toutes Paired Box 3 (PAX3) Anticorps
- Paired Box 3 (PAX3)
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache)
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Paired Box 3 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Séquence
- TTLAGAVPRM M-C
- Specificité
- This antibody detects PAX3 at N-term. This antibody is expected to recognise all 7 reported human isoforms (as represented by NP_000429.2, NP_039230.1, NP_852122.1,.1 NP_852123.1, NP_852124.1, NP_852125.1 and NP_852126.1).
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat and Cow.
Species reactivity (tested):Human. - Purification
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- Immunogène
- Peptide from the N Terminus of the protein sequence according to NP_000429.2, NP_039230.1, NP_852122.1,.1 NP_852123.1, NP_852124.1, NP_852125.1, NP_852126.1. Genename: PAX3
- Top Product
- Discover our top product PAX3 Anticorps primaire
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- Indications d'application
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Peptide ELISA: Antibody Limit Dilution: 1/64000. Western blot: Preliminary experiments gave an approx 30-35 kDa band in Human Kidneylysates at 1 μg/mL. Immunohistochemistry: 3 μg/mL. In paraffin embedded Human Oesophagus showsnuclear staining of cells in the Squamous Epithelium.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
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- Antigène
- Paired Box 3 (PAX3)
- Autre désignation
- PAX3 (PAX3 Produits)
- Synonymes
- anticorps PAX3, anticorps cdhs, anticorps hup2, anticorps pax-3, anticorps ws1, anticorps xpax3, anticorps Pax3, anticorps pax3, anticorps pax3b, anticorps xPax3-B, anticorps CDHS, anticorps HUP2, anticorps WS1, anticorps WS3, anticorps Pax-3, anticorps Sp, anticorps splotch, anticorps zgc:92547, anticorps paired box 3, anticorps paired box 3 L homeolog, anticorps paired box 3a, anticorps PAX3, anticorps pax3, anticorps pax3.L, anticorps Pax3, anticorps pax3a
- Sujet
- This protein is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These proteins play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.Synonyms: HUP2, Paired box protein Pax-3, Pax-3
- ID gène
- 5077
- NCBI Accession
- NP_000429
- UniProt
- P23760
- Pathways
- Sensory Perception of Sound, Tube Formation
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