GPX4 anticorps (C-Term, Isoform A)
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- Antigène Voir toutes GPX4 Anticorps
- GPX4 (Glutathione Peroxidase 4 (GPX4))
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Épitope
- C-Term, Isoform A
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Porc
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GPX4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody is expected to recognize isoform A (NP_002076.2) and isoform C (NP_001034937.1).
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Pig, Cow.
Species reactivity (tested):Human. - Purification
- Affinity Chromatpography
- Immunogène
- Peptide with sequence (C-EEPLVIEKDLPHY) from the C-terminus of the protein sequencen (NP_002076.2, NP_001034937.1).
- Top Product
- Discover our top product GPX4 Anticorps primaire
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- Indications d'application
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ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- GPX4 (Glutathione Peroxidase 4 (GPX4))
- Autre désignation
- Glutathione Peroxidase 4 / GPX4 (GPX4 Produits)
- Synonymes
- anticorps GPx-4, anticorps GSHPx-4, anticorps MCSP, anticorps PHGPx, anticorps snGPx, anticorps snPHGPx, anticorps Phgpx, anticorps gpx-4, anticorps snGpx, anticorps cb563, anticorps cb691, anticorps PHGPxa, anticorps sb:cb563, anticorps zgc:92253, anticorps wu:fb82e03, anticorps 1700027O09Rik, anticorps mtPHGPx, anticorps ATGPX4, anticorps F11L15.5, anticorps glutathione peroxidase 4, anticorps GP-GPx4, anticorps glutathione peroxidase 4, anticorps glutathione peroxidase 4a, anticorps GPX4, anticorps Gpx4, anticorps gpx4a
- Sujet
- Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.Synonyms: GPx-4, Phospholipid hydroperoxide glutathione peroxidase mitochondrial
- ID gène
- 2879
- NCBI Accession
- NP_001034936
- UniProt
- P36969
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