PAX8 anticorps (Internal Region)
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- Antigène Voir toutes PAX8 Anticorps
- PAX8 (Paired Box 8 (PAX8))
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Épitope
- Internal Region
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Reactivité
- Humain
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAX8 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- C-AQPGSDKRKM DD
- Specificité
- This antibody detects PAX8. It is expected to recognise all reported isoforms (NP_003457.1, NP_039245.1, NP_039246.1, NP_039247.1, NP_054698.1).
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- Immunogène
- Peptide from the internal region of the protein sequence according to NP_003457.1, NP_039245.1, NP_039246.1, NP_039247.1, NP_054698.1 Genename: PAX8
- Top Product
- Discover our top product PAX8 Anticorps primaire
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- Indications d'application
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Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.5-1.5 μg/mL. Approx 48 kDa + 48 kDa bands observed in lysates of cell lineHEK293 (calculated MW of 48.8 kDa according to PAX8A, NP_003457.1 and 41.8 kDaaccording to PAX8B, NP_039245.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- Antigène
- PAX8 (Paired Box 8 (PAX8))
- Autre désignation
- PAX8 (PAX8 Produits)
- Synonymes
- anticorps PAX8, anticorps XPax-8, anticorps XPax8, anticorps pax-8, anticorps PAX-8, anticorps Pax-8, anticorps paired box 8, anticorps paired box 8 L homeolog, anticorps PAX8, anticorps pax8, anticorps Pax8, anticorps pax8.L
- Sujet
- This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.Synonyms: Paired box protein Pax-8, Pax-8
- ID gène
- 7849
- NCBI Accession
- NP_003457
- UniProt
- Q06710
- Pathways
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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