Neuroligin 2 anticorps (Internal Region)
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- Antigène Voir toutes Neuroligin 2 (NLGN2) Anticorps
- Neuroligin 2 (NLGN2)
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Épitope
- Internal Region
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Reactivité
- Humain, Rat, Souris, Chien
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Neuroligin 2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- C-NPPDTDIRDP GKK
- Specificité
- This antibody detects Neuroligin-2.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Canine (Dog).
Species reactivity (tested):Human, Rat. - Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
- Immunogène
- Peptide from the internal region of the protein sequence according to NP_065846.1 Genename: NLGN2
- Top Product
- Discover our top product NLGN2 Anticorps primaire
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- Indications d'application
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Peptide ELISA: antibody detection limit dilution 1: 8000. Western blot: Approx 90 kDa band observed in Human Pancreas lysates (calculated MW of90.0 kDa according to NP_065846.1). Recommended concentration: 1-3 μg/mL. An additional band of unknown identity was also consistently observed at 50 kDa. Thisband was successfully blocked by incubation with the immunising peptide. We wouldappreciate any feedback from people in the field - have any such results been reportedwith other antibodies/lysates? Have any further splice variants/modified forms beenreported?
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- Neuroligin 2 (NLGN2)
- Autre désignation
- Neuroligin-2 (NLGN2 Produits)
- Synonymes
- anticorps Nlgn2, anticorps GB10066, anticorps NLGN2, anticorps CCE-L2, anticorps NV50031, anticorps Nv123771, anticorps NL2, anticorps RP23-422L16.24, anticorps neuroligin 2, anticorps LOC410779, anticorps NLGN2, anticorps LOC663865, anticorps LOC100123771, anticorps Nlgn2
- Sujet
- Neuroligins are cell adhesion proteins that are thought to instruct the formation and alignment of synaptic specializations. The three known rodent neuroligin isoforms share homologous extracellular acetylcholinesterase-like domains that bridge the synaptic cleft and bind beta-neurexins. All neuroligins have identical intracellular C-terminal motifs that bind to PDZ domains of various target proteins. Neuroligin 2 is exclusively localized to inhibitory synapses in rat brain and dissociated neurons. In immature neurons, neuroligin 2 is found at synapses and also at GABAA receptor aggregates that are not facing presynaptic termini.Synonyms: KIAA1366, NLGN2
- ID gène
- 57555, 9606
- UniProt
- Q8NFZ4
- Pathways
- Cell-Cell Junction Organization, Synaptic Membrane
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