BAG5 anticorps (Internal Region)
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- Antigène Voir toutes BAG5 Anticorps
- BAG5 (BCL2-Associated Athanogene 5 (BAG5))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BAG5 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody reacts to BAG5. This antibody is expected to recognise reported isoform a and isoform b.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Immunogène
- Peptide with sequence DPQGEEKCKAARKQ, from the internal region of the protein sequence
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- Discover our top product BAG5 Anticorps primaire
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- Indications d'application
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- BAG5 (BCL2-Associated Athanogene 5 (BAG5))
- Autre désignation
- BAG5 (BAG5 Produits)
- Synonymes
- anticorps BAG-5, anticorps bag-5, anticorps 1600025G07Rik, anticorps 4930405J06Rik, anticorps zgc:114117, anticorps BAG5, anticorps ATBAG5, anticorps BCL-2-associated athanogene 5, anticorps F12F1.7, anticorps F12F1_7, anticorps BCL2 associated athanogene 5, anticorps BCL2-associated athanogene 5, anticorps BCL-2-associated athanogene 5, anticorps BAG5, anticorps bag5, anticorps Bag5
- Sujet
- BAG5 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. A BAG domain near the C terminus, may bind and inhibit the chaperone activity of Hsc70/Hsp70. It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti apoptotic function. It is believed that BAG5 will play an important role in the mechanisms of neuronal death. BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.Synonyms: BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, KIAA0873
- ID gène
- 9529, 9606
- UniProt
- Q9UL15
- Pathways
- SARS-CoV-2 Protein Interactome
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