MBNL1 anticorps (C-Term)
-
- Antigène Voir toutes MBNL1 Anticorps
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
-
Épitope
- C-Term
-
Reactivité
- Humain, Rat, Souris, Chien, Boeuf (Vache)
-
Hôte
- Chèvre
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp MBNL1 est non-conjugé
-
Application
- Western Blotting (WB)
- Specificité
- This antibody reacts to MBNL1.
- Réactivité croisée (Details)
-
Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Immunogène
- Peptide with sequence C-SAEHLTSHKYVTQ, from the C Terminus of the protein sequence
- Top Product
- Discover our top product MBNL1 Anticorps primaire
-
-
- Indications d'application
-
Peptide ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 0,5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
- Autre désignation
- MBNL1 (MBNL1 Produits)
- Synonymes
- anticorps MBNL1, anticorps zgc:153954, anticorps Mbnl, anticorps mKIAA0428, anticorps EXP, anticorps EXP35, anticorps EXP40, anticorps EXP42, anticorps MBNL, anticorps muscleblind like splicing regulator 1, anticorps muscleblind-like splicing regulator 1, anticorps muscleblind like splicing factor 1, anticorps MBNL1, anticorps mbnl1, anticorps Mbnl1
- Sujet
- Muscleblind 1 (MBNL1) binds to the CUG triplet expansion in dsRNA. It appears to play a role in RNA splicing. Several important human diseases are associated with expansion of polynucleotide sequences, in most cases trinucleotide repeats. Myotonic dystrophy (DM1) is one of these diseases, and is associated with increases in the number of CTG repeats in the 3' UTR of the gene encoding myotonin (a.k.a. DM Kinase, DMK or myotonin-Protein Kinase), a ser/thr kinase expressed specifically in muscle. Mammalian genomes contain three muscleblind-like proteins, generally referred to as MBNL1, MBNL2 and MBNL3, and all three were found to associate with long double stranded CUG RNA repeats, thus being triplet repeat expansion dsRNA-binding proteins.Synonyms: EXP, Muscleblind-like protein 1
- ID gène
- 4154, 9606
- UniProt
- Q9NR56
- Pathways
- Ribonucleoprotein Complex Subunit Organization
-