This antibody is expected to recognise both reported isoforms (NP_000925.2, NP_001159393.1). Reported variants represent identical protein (NP_000925.2, NP_001159392.1).
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Immunogène
Peptide with sequence from the internal region of the protein sequence according to NP_000925.2, NP_001159393.1. Genename: SERPINF2
Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL. Immunohistochemistry on paraffin sections: 3 - 5 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
anticorps A2AP, anticorps AAP, anticorps ALPHA-2-PI, anticorps API, anticorps PLI, anticorps serpin, anticorps AI747498, anticorps Pli, anticorps Serpimf2, anticorps serpinf2, anticorps serpinf2l, anticorps wu:fd57d08, anticorps Dmrs91, anticorps Pedf, anticorps serpin family F member 2, anticorps serpin family F member 1, anticorps serine (or cysteine) peptidase inhibitor, clade F, member 2, anticorps serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a, anticorps SERPINF2, anticorps Serpinf2, anticorps SERPINF1, anticorps serpinf2a, anticorps Serpinf1
Sujet
Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. The protein has a major role in regulating the blood clotting pathway. Mutations result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: AAP, Alpha-2-AP, Alpha-2-PI, Alpha-2-plasmin inhibitor, PLI, Serpin F2