BIN1 anticorps (Internal Region)
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- Antigène Voir toutes BIN1 Anticorps
- BIN1 (Bridging Integrator 1 (BIN1))
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Épitope
- Internal Region
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Reactivité
- Humain
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BIN1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to BIN1.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Immunogène
- Peptide with sequence C-SDNAPAKGNKSPS, from the internal region of the protein sequence
- Top Product
- Discover our top product BIN1 Anticorps primaire
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- Indications d'application
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Peptide ELISA: 1/1000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- BIN1 (Bridging Integrator 1 (BIN1))
- Autre désignation
- BIN1 / AMPHL (BIN1 Produits)
- Synonymes
- anticorps bin1, anticorps MGC53185, anticorps amph2, anticorps amphl, anticorps sh3p9, anticorps MGC76187, anticorps cb57, anticorps zgc:86701, anticorps BIN1, anticorps AMPH2, anticorps AMPHL, anticorps SH3P9, anticorps ALP-1, anticorps Amphl, anticorps BRAMP-2, anticorps bridging integrator 1, anticorps bridging integrator 1 S homeolog, anticorps bridging integrator 1b, anticorps BIN1, anticorps bin1.S, anticorps bin1, anticorps bin1b, anticorps Bin1
- Sujet
- The identification and analysis of tumor suppressors is of major importance for improved diagnosis and treatment of tumors. Bin1 (Box-dependent myc interacting protein 1, also known as SH3P9, amphiphysin II and amphl/amphiphysin-like) is a novel protein that has features of a tumor suppressor. Bin1 interacts with and inhibits the oncogenic activity of the myc oncoprotein that has a major role in many human cancers. The loss of Bin1 may contribute to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver. Bin1 also interacts with HCV NS5A through its SH3 domain.Synonyms: Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Myc box-dependent-interacting protein 1
- ID gène
- 274
- NCBI Accession
- NP_004296
- UniProt
- O00499
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