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CD32/CD16 anticorps (PE-Cy7)

CD32/CD16 Reactivité: Souris FACS Hôte: Rat Monoclonal 93 PE-Cy7
N° du produit ABIN376639
  • Antigène Tous les produits CD32/CD16
    CD32/CD16
    Reactivité
    Souris
    Hôte
    • 54
    • 1
    • 1
    Rat
    Clonalité
    • 51
    • 1
    • 1
    Monoclonal
    Conjugué
    • 17
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD32/CD16 est conjugé à/à la PE-Cy7
    Application
    • 50
    • 11
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    Mouse CD16/32
    Attributs du produit
    Rat Anti-Mouse CD16/32-PE/CY7
    Purification
    Affinity chromatography
    Immunogène
    VH81X Tg B cells and T220 stromal cell line
    Clone
    93
    Isotype
    IgG2a
  • Indications d'application
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 3 g/106 cells FITC and BIOT conjugates 3 g/106 cells PE, APC, SPRD, PE/CY5.5, and PE/CY7 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Commentaires

    Blocking of g receptors

    Volume d'échantillon
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C
  • Antigène
    CD32/CD16
    Autre désignation
    CD16/32 (CD32/CD16 Produits)
    Sujet
    The lymphocyte Fc γ receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fc γ type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression. Besides identifying Fc γ R + cells, monoclonal antibodies to the Fc γ II/III receptor have been used to block Fc receptor binding of IgG, Fc- mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on Fc γ R for parasitic invasion.
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