SOX2 anticorps

N° du produit ABIN387798

Détail du produit anti-SOX2 anticorps

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOX2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: SOX2 recombinant protein is used to produce this monoclonal antibody.

Clone: 57CT23-3-4

Isotype: IgG1

Information d'application

Indications d'application: IF: 1:100. IF: 1:10~50. WB: 1:200~2000. WB: 1:200~2000. WB: 1:1000. WB: 1:4000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Références pour anticorps anti-SOX2 (ABIN387798)

Chen, Ou, Song, Xian, Ouyang, Xie, Xue, Sun: "Generation of integration-free induced pluripotent stem cells (GZHMUi001-A) by reprogramming peripheral blood mononuclear cells from a 47, XXX syndrome patient." dans: Stem cell research, Vol. 23, pp. 57-60, (2018) (PubMed).

Horibe, Hirohashi, Asano, Mariya, Suzuki, Takaya, Saijo, Shionoya, Kubo, Nakatsugawa, Kanaseki, Tsukahara, Watanabe, Atsuyama, Toji, Hirano, Hasegawa, Takahashi, Sato, Torigoe: "Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy." dans: PLoS ONE, Vol. 12, Issue 3, pp. e0171460, (2017) (PubMed).

Zheng, Pang, Gu, Gao, Zhang, Pang, Liu: "Melatonin Inhibits Glioblastoma Stem-like cells through Suppression of EZH2-NOTCH1 Signaling Axis." dans: International journal of biological sciences, Vol. 13, Issue 2, pp. 245-253, (2017) (PubMed).

Tilson, Haley, Triantafillu, Dozier, Langford, Gillespie, Kim: "ROCK Inhibition Facilitates In Vitro Expansion of Glioblastoma Stem-Like Cells." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0132823, (2015) (PubMed).

Détails sur SOX2

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Autre désignation: SOX2 (SOX2 Produits)

Sujet: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Poids moléculaire: 34310

ID gène: 6657

NCBI Accession: NP_003097

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis