Src anticorps

N° du produit ABIN387822

Détail du produit anti-Src anticorps

Antigène: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Src est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This Src antibody is generated from mouse immunized with a recombinant protein of full length human SRC.

Clone: 17AT28

Isotype: IgG1

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:500. WB: 1:2000. WB: 1:100~500. WB: 1:100~500. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Src (ABIN387822)

Nicholson, Seta, Lee, Morgan: "MicroRNA-203 mimics age-related aortic smooth muscle dysfunction of cytoskeletal pathways." dans: Journal of cellular and molecular medicine, Vol. 21, Issue 1, pp. 81-95, (2017) (PubMed).

Marcotte, Smith, Sanguin-Gendreau, McDonough, Muller: "Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 8, pp. 2808-13, (2012) (PubMed).

Chen, Li, Zhang, Yi, Chen, Wang, Zhang: "Src-stimulated IRTKS phosphorylation enhances cell migration." dans: FEBS letters, Vol. 585, Issue 19, pp. 2972-8, (2011) (PubMed).

Détails sur Src

Antigène: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Autre désignation: Src (Src Produits)

Synonymes: anticorps AW259666, anticorps pp60c-src, anticorps C-src1, anticorps CG7524, anticorps D-Src64B, anticorps D-src, anticorps DSRC64, anticorps DSrc, anticorps DSrc64, anticorps DSrc64B, anticorps Dm SRC1, anticorps DmHD-358, anticorps Dmel\CG7524, anticorps Dsrc, anticorps Dsrc64, anticorps Dsrc64B, anticorps HD-358, anticorps MRE5, anticorps SRC 64B, anticorps Src, anticorps Src1, anticorps Src64, anticorps c-src, anticorps dSrc, anticorps dsrc, anticorps src, anticorps src1, anticorps src64, anticorps src64B, anticorps src64b, anticorps ASV, anticorps SRC1, anticorps c-SRC, anticorps p60-Src, anticorps c-Src, anticorps PP60C-SCR, anticorps SDR, anticorps SRC proto-oncogene, non-receptor tyrosine kinase, anticorps uncharacterized LOC5574802, anticorps proto-oncogene tyrosine-protein kinase src, anticorps Rous sarcoma oncogene, anticorps Src oncogene at 64B, anticorps SRC, anticorps LOC5574802, anticorps CpipJ_CPIJ010659, anticorps Src, anticorps Src64B

Classe de substances: Viral Protein

Sujet: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 59835

ID gène: 6714

NCBI Accession: NP_005408, NP_938033

UniProt: P12931

Pathways: Signalistation JAK/STAT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling