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JMJD2D anticorps (C-Term)

KDM4D Reactivité: Humain WB Hôte: Lapin Polyclonal RB10797 unconjugated
N° du produit ABIN387871
  • Antigène Voir toutes JMJD2D (KDM4D) Anticorps
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Épitope
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 484-516, C-Term
    Reactivité
    • 33
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 33
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp JMJD2D est non-conjugé
    Application
    • 22
    • 18
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This JMJD2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-516 amino acids from the C-terminal region of human JMJD2D.
    Clone
    RB10797
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KDM4D Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Autre désignation
    JMJD2D (KDM4D Produits)
    Synonymes
    anticorps JMJD2D, anticorps 4932416A15, anticorps Jmjd2d, anticorps KDM4D, anticorps lysine demethylase 4D, anticorps lysine-specific demethylase 4D, anticorps lysine (K)-specific demethylase 4D, anticorps KDM4D, anticorps LOC524768, anticorps Kdm4d, anticorps LOC617971, anticorps LOC100067461, anticorps LOC698455, anticorps LOC100514356
    Sujet
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    Poids moléculaire
    58603
    ID gène
    55693
    NCBI Accession
    NP_060509
    UniProt
    Q6B0I6
    Pathways
    L'effet Warburg
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