This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-431 amino acids from the C-terminal region of human ENT1.
anticorps ENT1, anticorps rENT1, anticorps 1200014D21Rik, anticorps AA407560, anticorps solute carrier family 29 member 1 (Augustine blood group), anticorps solute carrier family 29 member 1, anticorps solute carrier family 29 (nucleoside transporters), member 1, anticorps SLC29A1, anticorps Slc29a1
Sujet
ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.