HDAC7 anticorps (C-Term)

N° du produit ABIN387957

Détail du produit anti-HDAC7 anticorps

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Épitope: AA 920-952, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC7 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This HDAC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 920-952 amino acids from the C-terminal region of human HDAC7.

Clone: RB5656

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur HDAC7

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Autre désignation: HDAC7 (HDAC7 Produits)

Synonymes: anticorps HD7A, anticorps HDAC7A, anticorps 5830434K02Rik, anticorps HD7, anticorps HD7a, anticorps Hdac7a, anticorps mFLJ00062, anticorps hdac7a, anticorps K2K18.5, anticorps K2K18_5, anticorps histone deacetylase7, anticorps histone deacetylase 7, anticorps histone deacetylase7, anticorps HDAC7, anticorps Hdac7, anticorps hdac7, anticorps HDA7

Sujet: Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the eta-amino groups of lysines located near the amino termini of core histone proteins (1). Eight members of HDAC family have been identified in the past several years (2,3). These HDAC family members are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93 % identity in amino acid sequence. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger than those of the class I members, and the deacetylase domains are present within the C-terminal regions, except that HDAC-6 contains two copies of the domain, one within each of the N-terminal and C-terminal regions. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns (3). These results suggested that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo.

Poids moléculaire: 102927

ID gène: 51564

NCBI Accession: NP_001091886, NP_056216

UniProt: Q8WUI4

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development