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HDAC11 anticorps (N-Term)

HDAC11 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB2588 unconjugated
N° du produit ABIN387964
  • Antigène Voir toutes HDAC11 Anticorps
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    Épitope
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivité
    • 48
    • 43
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 58
    • 5
    Lapin
    Clonalité
    • 60
    • 3
    Polyclonal
    Conjugué
    • 36
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HDAC11 est non-conjugé
    Application
    • 53
    • 33
    • 22
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC11.
    Clone
    RB2588
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Janssen, Schmalbach, Boeselt, Sarlette, Dengler, Petri: "Differential histone deacetylase mRNA expression patterns in amyotrophic lateral sclerosis." dans: Journal of neuropathology and experimental neurology, Vol. 69, Issue 6, pp. 573-81, (2010) (PubMed).

  • Antigène
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    Autre désignation
    HDAC11 (HDAC11 Produits)
    Synonymes
    anticorps CG31119, anticorps DHDACX, anticorps Dmel\\CG31119, anticorps HDAC11, anticorps HDACX, anticorps dHDAC11, anticorps dmHDA403, anticorps zgc:91942, anticorps HD11, anticorps histone deacetylase 11, anticorps Histone deacetylase 11, anticorps hypothetical protein, anticorps HDAC11, anticorps hdac11, anticorps CpipJ_CPIJ001619, anticorps Bm1_15905, anticorps LOAG_18214, anticorps Hdac11
    Sujet
    HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.
    Poids moléculaire
    39183
    ID gène
    79885
    NCBI Accession
    NP_001129513, NP_079103
    UniProt
    Q96DB2
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