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JAK2 anticorps (C-Term)

Name: JAK2 anticorps (C-Term)
SKU: ABIN387982
Price: 467.5 EUR
Availability: InStock

JAK2 Reactivité: Humain, Souris WB, FACS, IF Hôte: Lapin Polyclonal RB02956 unconjugated

The anti-JAK2 Pab (ABIN387982 and ABIN2844820) is used in Western blot to detect JAK2 in mouse thymus tissue lysate. (JAK2 anticorps (C-Term))

JAK2 Antibody (C-term) (ABIN387982 and ABIN2844820) flow cytometric analysis of K562 cells (right histogram) compared to a negative control (PBS alone) (left histogram). (JAK2 anticorps (C-Term))

FACS

Confocal immunofluorescent analysis of JAK2 Antibody (C-term) (ABIN387982 and ABIN2844820) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (JAK2 anticorps (C-Term))

3 images

(3 références)

N° du produit ABIN387982

Fiche de données

Antigène Voir toutes JAK2 Anticorps

JAK2 (Janus Kinase 2 (JAK2))
Épitope
29

27

16

16

6

6

6

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1101-1132, C-Term
Reactivité
142

85

84

18

18

3

2

2

1
Humain, Souris
Hôte
143

6

1
Lapin
Anticorps secondaires appropriés
Clonalité
131

19
Polyclonal
Conjugué
84

10

7

4

4

3

3

3

3

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1
Cet anticorp JAK2 est non-conjugé
Application
116

72

52

50

29

27

23

19

15

10

10

4

4

2

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène

This JAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1101-1132 amino acids from the C-terminal region of human JAK2.

Clone

RB02956

Isotype

Ig Fraction

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JAK2 Reactivité: Humain, Rat, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr1007), (pTyr1008) antibody
JAK2 Reactivité: Humain WB, ELISA, IHC, IP Hôte: Lapin Monoclonal 1A4 unconjugated Recombinant Antibody

anti-Janus Kinase 2 (JAK2) (C-Term) antibody
JAK2 Reactivité: Humain, Rat, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (AA 1101-1132) antibody
JAK2 Reactivité: Humain, Souris WB, ELISA, FACS, IF Hôte: Lapin Polyclonal unconjugated

Indications d'application

IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Feng, Chen, Wang, Cheng, Zou, Zhong, Xu: "Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 97, Issue 9, pp. 1008-1019, (2017) (PubMed).

Zhao, Li, Liao, Luo, Shi, Feng, Chen: "Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells." dans: International journal of molecular sciences, Vol. 16, Issue 11, pp. 27411-21, (2015) (PubMed).

Kanda, Watanabe: "Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes." dans: Endocrinology, Vol. 148, Issue 5, pp. 2317-25, (2007) (PubMed).
Antigène

JAK2 (Janus Kinase 2 (JAK2))

Autre désignation

JAK2 (JAK2 Produits)

Sujet

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Poids moléculaire

130674

ID gène

3717

NCBI Accession

NP_004963

UniProt

O60674

Pathways

Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response