KDM3A anticorps (N-Term)

N° du produit ABIN387995

Détail du produit anti-KDM3A anticorps

Antigène: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Épitope: AA 50-79, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM3A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This JHDM2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human JHDM2a.

Clone: RB14307

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur KDM3A

Antigène: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Autre désignation: JHDM2a (KDM3A Produits)

Synonymes: anticorps JHDM2A, anticorps JHMD2A, anticorps JMJD1, anticorps JMJD1A, anticorps TSGA, anticorps tsga, anticorps jmjd1, anticorps jhdm2a, anticorps jhmd2a, anticorps jmjd1a, anticorps 1700105C21Rik, anticorps C230043E16Rik, anticorps JHDM2a, anticorps Jmjd1, anticorps Jmjd1a, anticorps KDM2A, anticorps TGSA, anticorps Tsga, anticorps mKIAA0742, anticorps KDM3A, anticorps kdm3a, anticorps lysine demethylase 3A, anticorps lysine (K)-specific demethylase 3A, anticorps lysine-specific demethylase 3A, anticorps lysine (K)-specific demethylase 3A S homeolog, anticorps KDM3A, anticorps kdm3a, anticorps Kdm3a, anticorps LOC100453519, anticorps kdm3a.S

Sujet: JHDM2a is a zinc finger protein that contains a jumonji domain. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. This protein preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. It is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation.

Poids moléculaire: 147341

ID gène: 55818

NCBI Accession: NP_001140160, NP_060903

UniProt: Q9Y4C1

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, L'effet Warburg