HRK anticorps (AA 15-50)
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- Antigène Voir toutes HRK Anticorps
- HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
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Épitope
- AA 15-50
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HRK est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This Hrk BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-50 amino acids from human Hrk BH3 Domain.
- Clone
- RB04688
- Isotype
- Ig Fraction
- Top Product
- Discover our top product HRK Anticorps primaire
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- Indications d'application
- WB: 1:1000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
- Autre désignation
- Hrk (HRK Produits)
- Synonymes
- anticorps DP5, anticorps HARAKIRI, anticorps AI838259, anticorps Bid3, anticorps harakiri, anticorps Dp5, anticorps harakiri, BCL2 interacting protein, anticorps harakiri, BCL2 interacting protein (contains only BH3 domain), anticorps HRK, anticorps Hrk
- Sujet
- Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL.
- Poids moléculaire
- 9884
- ID gène
- 8739
- NCBI Accession
- NP_003797
- UniProt
- O00198
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