ATG3 anticorps (N-Term)
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- Antigène Voir toutes ATG3 Anticorps
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
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Épitope
- AA 2-31, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ATG3 est non-conjugé
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Application
- Western Blotting (WB)
- Homologie
- B, M, Rat, X
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This ATG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human ATG3.
- Clone
- RB7456
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ATG3 Anticorps primaire
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- Indications d'application
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
- Autre désignation
- ATG3 (ATG3 Produits)
- Synonymes
- anticorps atg3, anticorps im:6910145, anticorps wu:fb15g12, anticorps zgc:64156, anticorps APG3, anticorps APG3-LIKE, anticorps APG3L, anticorps PC3-96, anticorps 2610016C12Rik, anticorps Apg3l, anticorps Atg3l, anticorps PIG-1, anticorps Pig1, anticorps ATATG3, anticorps K11J9.1, anticorps K11J9_1, anticorps autophagy related 3, anticorps autophagy 3 (APG3), anticorps similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy, anticorps atg3, anticorps ATG3, anticorps Atg3
- Sujet
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.
- Poids moléculaire
- 35864
- ID gène
- 64422
- NCBI Accession
- NP_001265641, NP_071933
- UniProt
- Q9NT62
- Pathways
- Autophagy
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