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ATG4D anticorps (AA 220-249)

ATG4D Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB7565 unconjugated
N° du produit ABIN388509
  • Antigène Voir toutes ATG4D Anticorps
    ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
    Épitope
    • 15
    • 15
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 220-249
    Reactivité
    • 61
    • 41
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 78
    • 13
    • 1
    Lapin
    Clonalité
    • 79
    • 13
    Polyclonal
    Conjugué
    • 28
    • 8
    • 8
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATG4D est non-conjugé
    Application
    • 79
    • 37
    • 26
    • 26
    • 21
    • 15
    • 13
    • 6
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Pig
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This ATG4D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the Central region of human ATG4D.
    Clone
    RB7565
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ATG4D Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
    Autre désignation
    ATG4D (ATG4D Produits)
    Synonymes
    anticorps APG4-D, anticorps APG4D, anticorps AUTL4, anticorps 9830134P12Rik, anticorps Apg4d, anticorps Atg4dl, anticorps Autl4, anticorps apg4d, anticorps autophagy related 4D cysteine peptidase, anticorps autophagy related 4D, cysteine peptidase, anticorps autophagy related 4D, cysteine peptidase L homeolog, anticorps ATG4D, anticorps Atg4d, anticorps atg4d.L
    Sujet
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
    Poids moléculaire
    52922
    ID gène
    84971
    NCBI Accession
    NP_001268433, NP_116274
    UniProt
    Q86TL0
    Pathways
    Autophagy
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