UVRAG anticorps (AA 120-152)

N° du produit ABIN388588

Détail du produit anti-UVRAG anticorps

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Épitope: AA 120-152

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UVRAG est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This UVRAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-152 amino acids from human UVRAG.

Clone: RB10846

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: Tested. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur UVRAG

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Autre désignation: UVRAG (UVRAG Produits)

Synonymes: anticorps DHTX, anticorps VPS38, anticorps p63, anticorps 9530039D02Rik, anticorps AI648770, anticorps BB124205, anticorps Uvrag1, anticorps Uvragl, anticorps zgc:56164, anticorps uvrag, anticorps MGC81810, anticorps UVRAG, anticorps MGC131135, anticorps CG6116, anticorps Dmel\\CG6116, anticorps UV radiation resistance associated, anticorps UV radiation resistance associated gene, anticorps UV radiation resistance associated S homeolog, anticorps UV radiation resistance associated L homeolog, anticorps UV-resistance associated gene, anticorps UVRAG, anticorps Uvrag, anticorps uvrag, anticorps uvrag.S, anticorps uvrag.L

Sujet: UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.

Poids moléculaire: 78151

ID gène: 7405

NCBI Accession: NP_003360

UniProt: Q9P2Y5