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ACO2 anticorps (AA 438-467)

ACO2 Reactivité: Humain, Rat WB, IHC (p) Hôte: Lapin Polyclonal RB9338 unconjugated
N° du produit ABIN388648
  • Antigène Voir toutes ACO2 Anticorps
    ACO2 (Aconitase 2, Mitochondrial (ACO2))
    Épitope
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 438-467
    Reactivité
    • 60
    • 37
    • 36
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 51
    • 5
    • 4
    Lapin
    Clonalité
    • 46
    • 14
    Polyclonal
    Conjugué
    • 35
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp ACO2 est non-conjugé
    Application
    • 39
    • 25
    • 18
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B, M, Pig
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This ACO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 amino acids from the Central region of human ACO2.
    Clone
    RB9338
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ACO2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Ruiz, Bégou, Launay, Ranea-Robles, Bianchi, López-Erauskin, Morató, Guilera, Petit, Vaurs-Barriere, Guéret-Gonthier, Bonnet-Dupeyron, Fourcade, Auwerx, Boespflug-Tanguy, Pujol: "Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease." dans: Brain pathology (Zurich, Switzerland), (2017) (PubMed).

    Navarro, Botella, Metzendorf, Lind, Schneuwly: "Mitoferrin modulates iron toxicity in a Drosophila model of Friedreich?s ataxia." dans: Free radical biology & medicine, Vol. 85, pp. 71-82, (2015) (PubMed).

    Fernandes, Uytterhoeven, Kuenen, Wang, Slabbaert, Swerts, Kasprowicz, Aerts, Verstreken: "Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky-induced neurodegeneration." dans: The Journal of cell biology, Vol. 207, Issue 4, pp. 453-62, (2014) (PubMed).

    Maity, Bindu, Dey, Goyal, Alam, Pal, Mitra, Bandyopadhyay et al.: "Indomethacin, a non-steroidal anti-inflammatory drug, develops gastropathy by inducing reactive oxygen species-mediated mitochondrial pathology and associated apoptosis in gastric mucosa: a novel ..." dans: The Journal of biological chemistry, Vol. 284, Issue 5, pp. 3058-68, (2009) (PubMed).

    OConnell, Gannon, Doran, Ohlendieck: "Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle." dans: International journal of molecular medicine, Vol. 20, Issue 2, pp. 145-53, (2007) (PubMed).

  • Antigène
    ACO2 (Aconitase 2, Mitochondrial (ACO2))
    Autre désignation
    ACO2 (ACO2 Produits)
    Synonymes
    anticorps DDBDRAFT_0206187, anticorps DDBDRAFT_0230168, anticorps DDB_0206187, anticorps DDB_0230168, anticorps aconitase 2, anticorps F10M23.310, anticorps F10M23_310, anticorps ACONM, anticorps ICRD, anticorps Aco-2, anticorps Aco3, anticorps D10Wsu183e, anticorps cb1017, anticorps wu:fa10e03, anticorps wu:fb69g04, anticorps wu:fc20c11, anticorps aconitase 2, anticorps aconitase 2 S homeolog, anticorps aconitate hydratase, mitochondrial, anticorps aconitase, mitochondrial, anticorps mitochondrial aconitate hydratase, anticorps aconitase 2, mitochondrial, anticorps Probable aconitate hydratase, mitochondrial, anticorps ACO2, anticorps aco2.S, anticorps Bm1_07420, anticorps aco2, anticorps ach1, anticorps Aco2, anticorps aco-2
    Sujet
    ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
    Poids moléculaire
    85425
    ID gène
    50
    NCBI Accession
    NP_001089
    UniProt
    Q99798
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