NEUROD1 anticorps (C-Term)

N° du produit ABIN388766

Détail du produit anti-NEUROD1 anticorps

Antigène: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Épitope: AA 318-348, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEUROD1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This NeuroD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-348 amino acids from the C-terminal region of human NeuroD1.

Clone: RB02904

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur NEUROD1

Antigène: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Autre désignation: NeuroD1 (NEUROD1 Produits)

Synonymes: anticorps BETA2, anticorps BHF-1, anticorps MODY6, anticorps NEUROD, anticorps bHLHa3, anticorps Neurod, anticorps neurod, anticorps XNeuroD, anticorps MGC82572, anticorps NEUROD1, anticorps ND1, anticorps beta2, anticorps bhf-1, anticorps neuro-D, anticorps nrd, anticorps neuroD, anticorps neurod1, anticorps Beta2, anticorps neuronal differentiation 1, anticorps neurogenic differentiation 1, anticorps neuronal differentiation 1 S homeolog, anticorps neuronal differentiation 1 L homeolog, anticorps NEUROD1, anticorps Neurod1, anticorps neurod1.S, anticorps neurod1, anticorps neurod1.L

Sujet: NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.

Poids moléculaire: 39920

ID gène: 4760

NCBI Accession: NP_002491

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis