SOX4 anticorps (N-Term)

N° du produit ABIN388786

Détail du produit anti-SOX4 anticorps

Antigène: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Épitope: AA 86-114, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This SOX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the N-terminal region of human SOX4.

Clone: RB18502

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-SOX4 (ABIN388786)

Chen, Ruan, Wang, Han, Wang, Lou, Ruan, Qiu, Yang, Zhang: "miR-129-3p, as a diagnostic and prognostic biomarker for renal cell carcinoma, attenuates cell migration and invasion via downregulating multiple metastasis-related genes." dans: Journal of cancer research and clinical oncology, Vol. 140, Issue 8, pp. 1295-304, (2014) (PubMed).

Détails sur SOX4

Antigène: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Autre désignation: SOX4 (SOX4 Produits)

Synonymes: anticorps EVI16, anticorps AA682046, anticorps Sox-4, anticorps sox4, anticorps wu:fb82f08, anticorps wu:fq41g10, anticorps zgc:65850, anticorps zgc:77392, anticorps SRY-box 4, anticorps SRY box 4, anticorps SRY (sex determining region Y)-box 4, anticorps SRY (sex determining region Y)-box 4a, anticorps SOX4, anticorps Sox4, anticorps sox4a

Sujet: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.

Poids moléculaire: 47263

ID gène: 6659

NCBI Accession: NP_003098

UniProt: Q06945