SLUG anticorps (N-Term)

N° du produit ABIN388808

Détail du produit anti-SLUG anticorps

Antigène: SLUG

Épitope: AA 1-30, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLUG est non-conjugé

Application: Western Blotting (WB)

Homologie: B, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This SLUG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SLUG.

Clone: RB15389

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-SLUG (ABIN388808)

Liang, Wang, Li, Yu, Zhang, Li: "miR-33a suppresses the nuclear translocation of ?-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells." dans: Tumour biology, (2015) (PubMed).

Huo, Kao, Chuu: "Androgen receptor inhibits epithelial-mesenchymal transition, migration, and invasion of PC-3 prostate cancer cells." dans: Cancer letters, Vol. 369, Issue 1, pp. 103-11, (2015) (PubMed).

Huang, Chen, Chang, Yuan, Jeng: "Hepatocyte growth factor activates Wnt pathway by transcriptional activation of LEF1 to facilitate tumor invasion." dans: Carcinogenesis, Vol. 33, Issue 6, pp. 1142-8, (2012) (PubMed).

Collado, Thiede, Baker, Askew, Igbani, Corwin: "The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 33, pp. 11855-66, (2011) (PubMed).

Fu, Lv, Lin, Wu, Wang, Zhou, Zhang, Wang, Tsang, Zhu, Wang: "Ubiquitin ligase cullin 7 induces epithelial-mesenchymal transition in human choriocarcinoma cells." dans: The Journal of biological chemistry, Vol. 285, Issue 14, pp. 10870-9, (2010) (PubMed).

Détails sur SLUG

Antigène: SLUG

Abstract: SLUG Produits

Synonymes: anticorps Slug, anticorps Slugh, anticorps Snail2, anticorps SLUG, anticorps SLUGH, anticorps SLUGH1, anticorps SNAIL2, anticorps WS2D, anticorps snail family zinc finger 2, anticorps snail family transcriptional repressor 2, anticorps Snai2, anticorps SNAI2

Sujet: SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. This protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in the gene encoding SLUG may be associated with sporadic cases of neural tube defects.

Poids moléculaire: 29986

NCBI Accession: NP_003059

UniProt: O43623