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USP4 anticorps (C-Term)

USP4 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB4269 unconjugated
N° du produit ABIN388883
  • Antigène Voir toutes USP4 Anticorps
    USP4 (Ubiquitin Specific Peptidase 4 (USP4))
    Épitope
    • 15
    • 10
    • 9
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 903-933, C-Term
    Reactivité
    • 49
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 1
    • 1
    Lapin
    Clonalité
    • 48
    • 1
    Polyclonal
    Conjugué
    • 23
    • 6
    • 6
    • 6
    • 4
    • 4
    Cet anticorp USP4 est non-conjugé
    Application
    • 35
    • 34
    • 31
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This USP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 903-933 amino acids from the C-terminal region of human USP4.
    Clone
    RB4269
    Isotype
    Ig Fraction
    Top Product
    Discover our top product USP4 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Laurell, Velázquez-Fernández, Lindsten, Juhlin, Enberg, Geli, Höög, Kjellman, Lundeberg, Hamberger, Larsson, Nilsson, Bäckdahl: "Transcriptional profiling enables molecular classification of adrenocortical tumours." dans: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 141-52, (2009) (PubMed).

  • Antigène
    USP4 (Ubiquitin Specific Peptidase 4 (USP4))
    Autre désignation
    USP4 (USP4 Produits)
    Synonymes
    anticorps UNP, anticorps Unph, anticorps F730026I20Rik, anticorps Unp, anticorps mKIAA4155, anticorps ubiquitin specific peptidase 4, anticorps ubiquitin specific peptidase 4 (proto-oncogene), anticorps USP4, anticorps Usp4
    Sujet
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    Poids moléculaire
    108565
    ID gène
    7375
    NCBI Accession
    NP_001238806, NP_003354, NP_955475
    UniProt
    Q13107
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