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USP8 anticorps (C-Term)

USP8 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB04288 unconjugated
N° du produit ABIN388891
  • Antigène Voir toutes USP8 Anticorps
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Épitope
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1058-1087, C-Term
    Reactivité
    • 35
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 32
    • 2
    • 1
    Lapin
    Clonalité
    • 33
    • 2
    Polyclonal
    Conjugué
    • 25
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp USP8 est non-conjugé
    Application
    • 31
    • 15
    • 13
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This USP8 (UBPY) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1058-1087 amino acids from the C-terminal region of human USP8 (UBPY).
    Clone
    RB04288
    Isotype
    Ig Fraction
    Top Product
    Discover our top product USP8 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Autre désignation
    USP8 (UBPY) (USP8 Produits)
    Synonymes
    anticorps HumORF8, anticorps UBPY, anticorps AI574262, anticorps AW557536, anticorps Ubpy, anticorps mKIAA0055, anticorps ubiquitin carboxyl-terminal hydrolase 8, anticorps ubiquitin specific peptidase 8, anticorps LOC9310109, anticorps MGYG_00369, anticorps USP8, anticorps Usp8
    Sujet
    USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structur/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.
    Poids moléculaire
    127523
    ID gène
    9101
    NCBI Accession
    NP_001122082, NP_001122083, NP_005145
    UniProt
    P40818
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