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USP12 anticorps (N-Term)

USP12 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB4297 unconjugated
N° du produit ABIN388898
  • Antigène Voir toutes USP12 Anticorps
    USP12 (Ubiquitin Specific Peptidase 12 (USP12))
    Épitope
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 5-35, N-Term
    Reactivité
    • 42
    • 36
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 50
    • 4
    Lapin
    Clonalité
    • 53
    • 1
    Polyclonal
    Conjugué
    • 23
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp USP12 est non-conjugé
    Application
    • 42
    • 34
    • 9
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    X, B
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This USP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-35 amino acids from the N-terminal region of human USP12.
    Clone
    RB4297
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    USP12 (Ubiquitin Specific Peptidase 12 (USP12))
    Autre désignation
    USP12 (USP12 Produits)
    Synonymes
    anticorps UBH1, anticorps USP12L1, anticorps usp12, anticorps USP12P1, anticorps sb:eu882, anticorps wu:fi09d12, anticorps Ubh1, anticorps ubh1, anticorps usp12l1, anticorps ubiquitin specific peptidase 12, anticorps ubiquitin specific peptidase 12a, anticorps ubiquitin specific peptidase 12 L homeolog, anticorps ubiquitin specific peptidase 12 S homeolog, anticorps USP12, anticorps usp12, anticorps Usp12, anticorps usp12a, anticorps usp12.L, anticorps usp12.S
    Sujet
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    Poids moléculaire
    42858
    ID gène
    219333
    NCBI Accession
    NP_872294
    UniProt
    O75317
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