USP12 anticorps (N-Term)

N° du produit ABIN388898

Détail du produit anti-USP12 anticorps

Antigène: USP12 (Ubiquitin Specific Peptidase 12 (USP12))

Épitope: AA 5-35, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: X, B

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This USP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-35 amino acids from the N-terminal region of human USP12.

Clone: RB4297

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur USP12

Antigène: USP12 (Ubiquitin Specific Peptidase 12 (USP12))

Autre désignation: USP12 (USP12 Produits)

Synonymes: anticorps UBH1, anticorps USP12L1, anticorps usp12, anticorps USP12P1, anticorps sb:eu882, anticorps wu:fi09d12, anticorps Ubh1, anticorps ubh1, anticorps usp12l1, anticorps ubiquitin specific peptidase 12, anticorps ubiquitin specific peptidase 12a, anticorps ubiquitin specific peptidase 12 L homeolog, anticorps ubiquitin specific peptidase 12 S homeolog, anticorps USP12, anticorps usp12, anticorps Usp12, anticorps usp12a, anticorps usp12.L, anticorps usp12.S

Sujet: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Poids moléculaire: 42858

ID gène: 219333

NCBI Accession: NP_872294

UniProt: O75317