USP13 anticorps (AA 389-419)

N° du produit ABIN388901

Détail du produit anti-USP13 anticorps

Antigène: USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))

Épitope: AA 389-419

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP13 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This USP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the Central region of human USP13.

Clone: RB4304

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur USP13

Antigène: USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))

Autre désignation: USP13 (USP13 Produits)

Synonymes: anticorps ISOT3, anticorps IsoT-3, anticorps 2700071E21Rik, anticorps AI848077, anticorps usp13, anticorps MGC163140, anticorps ubiquitin specific peptidase 13, anticorps ubiquitin specific peptidase 13 (isopeptidase T-3), anticorps ubiquitin carboxyl-terminal hydrolase 13, anticorps universal stress protein, anticorps USP13, anticorps Usp13, anticorps usp13, anticorps MGYG_01656, anticorps RR_RS02895

Sujet: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Poids moléculaire: 97327

ID gène: 8975

NCBI Accession: NP_003931

UniProt: Q92995

Pathways: SARS-CoV-2 Protein Interactome