USP25 anticorps (N-Term)

N° du produit ABIN388917

Détail du produit anti-USP25 anticorps

Antigène: USP25 (Ubiquitin Specific Peptidase 25 (USP25))

Épitope: AA 133-163, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP25 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This USP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-163 amino acids from the N-terminal region of human USP25.

Clone: RB4364

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur USP25

Antigène: USP25 (Ubiquitin Specific Peptidase 25 (USP25))

Autre désignation: USP25 (USP25 Produits)

Synonymes: anticorps USP25, anticorps zgc:55791, anticorps wu:fi33c05, anticorps wu:fo67e06, anticorps wu:fp97a04, anticorps usp25, anticorps MGC81666, anticorps usp21, anticorps USP21, anticorps ubiquitin specific peptidase 25, anticorps universal stress protein UspA, anticorps ubiquitin specific peptidase 25 L homeolog, anticorps USP25, anticorps RR_RS03930, anticorps usp25, anticorps usp25.L, anticorps Usp25

Sujet: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Poids moléculaire: 122218

ID gène: 29761

NCBI Accession: NP_037528

UniProt: Q9UHP3