FNTA anticorps (AA 88-118)

N° du produit ABIN389057

Détail du produit anti-FNTA anticorps

Antigène: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Épitope: AA 88-118

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FNTA est non-conjugé

Application: Western Blotting (WB)

Homologie: B, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the Central region of human FNTA.

Clone: RB4792

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur FNTA

Antigène: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Autre désignation: FNTA (FNTA Produits)

Synonymes: anticorps ATFTA, anticorps FARNESYLTRANSFERASE A, anticorps FARNESYLTRANSFERASE SUBUNIT A, anticorps PFT/PGGT-IALPHA, anticorps PLP, anticorps PLURIPETALA, anticorps farnesyltransferase A, anticorps FPTA, anticorps PGGT1A, anticorps PTAR2, anticorps PFAS, anticorps FTA, anticorps farnesyltransferase A, anticorps farnesyltransferase, CAAX box, alpha, anticorps FTA, anticorps FNTA, anticorps Fnta

Sujet: FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.

Poids moléculaire: 44409

ID gène: 2339

NCBI Accession: NP_002018

UniProt: P49354

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling