PFDN6 anticorps (N-Term)

N° du produit ABIN389346

Détail du produit anti-PFDN6 anticorps

Antigène: PFDN6 (Prefoldin Subunit 6 (PFDN6))

Épitope: AA 6-34, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFDN6 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PFDN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human PFDN6.

Clone: RB17559

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PFDN6 (ABIN389346)

Tashiro, Zako, Muto, Itoo, Sörgjerd, Terada, Abe, Miyazawa, Kitamura, Kitaura, Kubota, Maeda, Momoi, Iguchi-Ariga, Kinjo, Ariga: "Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation." dans: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19958-72, (2013) (PubMed).

Abe, Takahashi-Niki, Takekoshi, Shimizu, Kitaura, Maita, Iguchi-Ariga, Ariga: "Prefoldin plays a role as a clearance factor in preventing proteasome inhibitor-induced protein aggregation." dans: The Journal of biological chemistry, Vol. 288, Issue 39, pp. 27764-76, (2013) (PubMed).

Miyazawa, Tashiro, Kitaura, Maita, Suto, Iguchi-Ariga, Ariga: "Prefoldin subunits are protected from ubiquitin-proteasome system-mediated degradation by forming complex with other constituent subunits." dans: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19191-203, (2011) (PubMed).

Détails sur PFDN6

Antigène: PFDN6 (Prefoldin Subunit 6 (PFDN6))

Autre désignation: PFDN6 (PFDN6 Produits)

Synonymes: anticorps hke2, anticorps ke-2, anticorps pfd6, anticorps h2-ke2, anticorps pfdn6a, anticorps 23.m05913, anticorps H-2Ke2, anticorps Ke-2, anticorps Pfdn6, anticorps H2-KE2, anticorps HKE2, anticorps KE-2, anticorps PFD6, anticorps zgc:66282, anticorps pfdn6, anticorps pfdn6b, anticorps Ke2, anticorps prefoldin subunit 6 S homeolog, anticorps prefoldin subunit 6 (predicted), anticorps prefoldin subunit 6, anticorps prefoldin subunit 6 L homeolog, anticorps pfdn6.S, anticorps SPAC3A11.13, anticorps BBOV_IV004800, anticorps AOR_1_2254174, anticorps CMU_042830, anticorps pfdn6, anticorps Pfdn6, anticorps PFDN6, anticorps pfdn6.L

Sujet: PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. This protein also binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Poids moléculaire: 14583

ID gène: 10471

NCBI Accession: NP_001172110, NP_001252524, NP_001252525, NP_055075

UniProt: O15212

Pathways: Unfolded Protein Response