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INPP5D anticorps (AA 770-796)

INPP5D Reactivité: Humain WB Hôte: Lapin Polyclonal RB17405 unconjugated
N° du produit ABIN389359
  • Antigène Voir toutes INPP5D Anticorps
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    Épitope
    • 18
    • 18
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 770-796
    Reactivité
    • 89
    • 66
    • 42
    • 20
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 85
    • 5
    Lapin
    Clonalité
    • 75
    • 15
    Polyclonal
    Conjugué
    • 31
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp INPP5D est non-conjugé
    Application
    • 57
    • 21
    • 18
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This INPP5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 770-796 amino acids from the Central region of human INPP5D.
    Clone
    RB17405
    Isotype
    Ig Fraction
    Top Product
    Discover our top product INPP5D Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    Autre désignation
    INPP5D (INPP5D Produits)
    Synonymes
    anticorps INPP5D, anticorps 256.t00004, anticorps 13.t00027, anticorps ship, anticorps ship1, anticorps AI323613, anticorps SHIP, anticorps SHIP-1, anticorps SHIP1, anticorps s-SHIP, anticorps SIP-145, anticorps hp51CN, anticorps inositol polyphosphate-5-phosphatase D, anticorps phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, anticorps inositol polyphosphate 5-phosphatase, anticorps inositol polyphosphate-5-phosphatase D L homeolog, anticorps INPP5D, anticorps LOC100446045, anticorps inpp5d, anticorps EHI_159880, anticorps EHI_153490, anticorps inpp5d.L, anticorps LOC100380693, anticorps Inpp5d
    Sujet
    INPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and it is a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival.
    Poids moléculaire
    133292
    ID gène
    3635
    NCBI Accession
    NP_001017915, NP_005532
    UniProt
    Q92835
    Pathways
    TCR Signaling, BCR Signaling, L'effet Warburg
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