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APEX1 anticorps (N-Term)

APEX1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal RB17544 unconjugated
N° du produit ABIN389367
  • Antigène Voir toutes APEX1 Anticorps
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    Épitope
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-64, N-Term
    Reactivité
    • 89
    • 43
    • 39
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 73
    • 18
    • 2
    Lapin
    Clonalité
    • 76
    • 17
    Polyclonal
    Conjugué
    • 64
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp APEX1 est non-conjugé
    Application
    • 79
    • 30
    • 27
    • 24
    • 18
    • 10
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This APEX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-64 amino acids from the N-terminal region of human APEX1.
    Clone
    RB17544
    Isotype
    Ig Fraction
    Top Product
    Discover our top product APEX1 Anticorps primaire
  • Indications d'application
    IF: 1:10~50. WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    Autre désignation
    APEX1 (APEX1 Produits)
    Synonymes
    anticorps apex1, anticorps MGC76280, anticorps MGC79645, anticorps MGC78928, anticorps APE, anticorps APE1, anticorps APEN, anticorps APEX, anticorps APX, anticorps HAP1, anticorps REF1, anticorps Apex, anticorps REF-1, anticorps BAP1, anticorps apex1a, anticorps hm:zehn1532, anticorps wu:fc13d11, anticorps zgc:66204, anticorps Ref-1, anticorps apurinic/apyrimidinic endodeoxyribonuclease 1, anticorps APEX nuclease (multifunctional DNA repair enzyme) 1, anticorps APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog, anticorps DNA-(apurinic or apyrimidinic site) lyase, anticorps apurinic/apyrimidinic endonuclease 1, anticorps APEX1, anticorps apex1, anticorps apex1.L, anticorps CNG03640, anticorps CNH01280, anticorps nth, anticorps Spirs_4119, anticorps Palpr_0103, anticorps Apex1
    Sujet
    Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This protein is the major AP endonuclease in human cells.
    Poids moléculaire
    35555
    ID gène
    328
    NCBI Accession
    NP_001231178, NP_001632, NP_542379, NP_542380
    UniProt
    P27695
    Pathways
    Réparation de l'ADN, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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