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PABP anticorps (AA 250-279)

PABPC1 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB20873 unconjugated
N° du produit ABIN389462
  • Antigène Voir toutes PABP (PABPC1) Anticorps
    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
    Épitope
    • 15
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 250-279
    Reactivité
    • 20
    • 20
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 32
    • 3
    Lapin
    Clonalité
    • 32
    • 3
    Polyclonal
    Conjugué
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PABP est non-conjugé
    Application
    • 28
    • 14
    • 14
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B, Rat, X
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This PABPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human PABPC1.
    Clone
    RB20873
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PABPC1 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
    Autre désignation
    PABPC1 (PABPC1 Produits)
    Synonymes
    anticorps PAB1, anticorps PABP, anticorps PABP1, anticorps PABPC2, anticorps PABPL1, anticorps Pabp1, anticorps PabpI, anticorps Pabpl1, anticorps ePAB, anticorps Pabp, anticorps pab1, anticorps pabp, anticorps pabp1, anticorps pabpc1, anticorps pabpc2, anticorps PABPC1, anticorps wu:fb16a02, anticorps wu:fi19b08, anticorps wu:fj12d09, anticorps wu:fj61f06, anticorps zgc:109879, anticorps zgc:77608, anticorps poly(A) binding protein cytoplasmic 1, anticorps poly(A) binding protein, cytoplasmic 1, anticorps poly(A) binding protein, cytoplasmic 1 S homeolog, anticorps poly(A) binding protein cytoplasmic 1 like, anticorps poly(A) binding protein, cytoplasmic 1 L homeolog, anticorps poly(A) binding protein, cytoplasmic 1a, anticorps poly A binding protein, cytoplasmic 1 b, anticorps PABPC1, anticorps Pabpc1, anticorps pabpc1.S, anticorps pabpc1, anticorps PABPC1L, anticorps pabpc1.L, anticorps pabpc1a, anticorps pabpc1b
    Sujet
    PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
    Poids moléculaire
    70671
    ID gène
    26986
    NCBI Accession
    NP_002559
    UniProt
    P11940
    Pathways
    SARS-CoV-2 Protein Interactome
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