Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This MAPKAPK5 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S93 of human MAPKAPK5.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Daily, Monks, Leggas, Moscow: "Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition." dans: Toxicon : official journal of the International Society on Toxinology, Vol. 55, Issue 4, pp. 827-37, (2010) (PubMed).
Antigène
MAPKAP Kinase 5 (MAPKAPK5)
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
anticorps MAPKAPK5, anticorps MK5, anticorps PRAK, anticorps MAPKAP-K5, anticorps MK-5, anticorps mitogen-activated protein kinase-activated protein kinase 5, anticorps MAP kinase-activated protein kinase 5, anticorps MAPKAPK5, anticorps mapkapk5, anticorps Mapkapk5
Sujet
The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites.