This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This MAP3K1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1400 of human MAP3K1.
MAP3K1
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
DB: 1:500
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Craig, Parker, Austin, Barnett, Camenisch: "Involvement of the MEKK1 signaling pathway in the regulation of epicardial cell behavior by hyaluronan." dans: Cellular signalling, Vol. 22, Issue 6, pp. 968-76, (2010) (PubMed).
Mokhtari, Myers, Welsh: "MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells." dans: Diabetes, Vol. 57, Issue 7, pp. 1896-904, (2008) (PubMed).
Antigène
MAP3K1
(Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.